Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 4/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | CDK1 | P06493 | 6/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171967 | 0.91 | SYK (0.51) | MERTKSYKAURKAKDRCDK1 | |
| SCHEMBL15584131 | 0.85 | FLT3 (0.60) | MERTKSYKAURKAKDRCDK1 | |
| SCHEMBL20172011 | 0.83 | KDR (0.41) | MERTKKDRCDK1FLT3EGFR | |
| SCHEMBL16450162 | 0.80 | SYK (0.58) | SYKAURKAFLT3MAPK9MAPK10 | |
| SCHEMBL15585214 | 0.80 | SYK (0.52) | SYKAURKAFLT3STK17A | |
| SCHEMBL15584553 | 0.79 | MERTK (0.49) | MERTKSYKAURKAKDRCDK1 | |
| SCHEMBL20171963 | 0.79 | SYK (0.49) | MERTKSYKAURKAKDRCDK1 | |
| SCHEMBL20172044 | 0.79 | FLT3 (0.54) | MERTKSYKAURKAKDRCDK1 | |
| SCHEMBL20172050 | 0.78 | SYK (0.51) | MERTKSYKAURKAFLT3MAPK9 | |
| SCHEMBL15584301 | 0.78 | SYK (0.51) | SYKAURKAFLT3MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323811-A1 | PRODUCTION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND INTERMEDIATE OF SAID NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM Corporation (JP) | 2018-05-23 | — | — | EP | disclosed |