Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.41 |
| ▸ | CDK1 | P06493 | 6/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171970 | 0.83 | MERTK (0.51) | KDRCDK1MERTKFLT3EGFR | |
| SCHEMBL20171967 | 0.74 | SYK (0.51) | KDRCDK1MERTKFLT3EGFR | |
| SCHEMBL15584131 | 0.69 | FLT3 (0.60) | KDRCDK1MERTKFLT3ABCG2 | |
| SCHEMBL20171959 | 0.65 | KDR (0.38) | KDRCDK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL15585214 | 0.65 | SYK (0.52) | FLT3NPC1RAB9A | |
| SCHEMBL16450162 | 0.65 | SYK (0.58) | FLT3NPC1RAB9A | |
| SCHEMBL7395296 | 0.63 | GABRP (0.47) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL7030337 | 0.63 | TSHR (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL81846 | 0.63 | TSHR (0.55) | CYP11B1CYP11B2 | |
| SCHEMBL20172044 | 0.63 | FLT3 (0.54) | KDRCDK1MERTKFLT3ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323811-B1 | PRODUCTION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND INTERMEDIATE OF SAID NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2019-05-08 | — | — | EP | disclosed |
| EP-3323811-A1 | PRODUCTION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND INTERMEDIATE OF SAID NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM Corporation (JP) | 2018-05-23 | — | — | EP | disclosed |