Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17178219 | 0.86 | DRD1 (0.44) | DRD1ALDH1A1CYP3A4GAALMNA | |
| SCHEMBL19390579 | 0.85 | MEN1 (0.41) | ALDH1A1KMT2AGAALMNA | |
| SCHEMBL19390602 | 0.81 | ACHE (0.43) | ACHEDRD1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL17174351 | 0.80 | DRD1 (0.40) | DRD1ALDH1A1KMT2APDE10A | |
| SCHEMBL15667486 | 0.73 | DRD1 (0.54) | DRD1CYP3A4KMT2A | |
| SCHEMBL26213974 | 0.73 | ACHE (0.47) | ACHEALDH1A1CYP3A4KMT2AGAA | |
| SCHEMBL15688327 | 0.71 | CYP1A1 (0.46) | DRD1ALDH1A1CYP3A4KMT2AGAA | |
| SCHEMBL16542335 | 0.70 | ACHE (0.58) | ACHEALDH1A1CYP3A4KMT2AALPL | |
| SCHEMBL15688326 | 0.70 | ESR1 (0.44) | DRD1KMT2AGAA | |
| SCHEMBL17133490 | 0.67 | ACHE (0.44) | ACHEALDH1A1CYP3A4KMT2APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323821-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | Pfizer Inc (US) | 2018-05-23 | — | — | EP | disclosed |