SCHEMBL26213974

SCHEMBL26213974

COc1cccc(OC)c1-c1ccc(C)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.47
ELANE P08246 1/20 0.44
ALDH1A1 P00352 4/20 0.42
CYP3A4 P08684 2/20 0.42
TOP1 P11387 1/20 0.42
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41
APAF1 O14727 1/20 0.41
MITF O75030 1/20 0.41
HTT P42858 1/20 0.41
HPGD P15428 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GAA P10253 2/20 0.41
MAPK1 P28482 2/20 0.40
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26212573 0.84 PDCD1 (0.43) ELANEALDH1A1GAAMAPK1POLB
SCHEMBL14363369 0.82 ACHE (0.54) ACHEALDH1A1CYP3A4TOP1LMNA
SCHEMBL24196871 0.81 MAPT (0.42) ELANEALDH1A1CYP3A4TOP1LMNA
SCHEMBL14850872 0.81 AKR1C3 (0.55) ACHEELANEALDH1A1CYP3A4MAPT
SCHEMBL5461155 0.78 ALDH1A1 (0.50) ELANEALDH1A1TOP1LMNAMAPT
SCHEMBL24557402 0.78 RAPGEF4 (0.44) ACHEELANEALDH1A1CYP3A4TOP1
SCHEMBL16542335 0.78 ACHE (0.58) ACHEALDH1A1CYP3A4LMNAMAPT
SCHEMBL1459479 0.78 ACHE (0.40) ACHEELANEALDH1A1CYP3A4LMNA
SCHEMBL31049807 0.77 PDK2 (0.46) ACHEELANEALDH1A1CYP3A4MAPT
SCHEMBL24196011 0.76 ELANE (0.49) ACHEELANEALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-26 US disclosed
US-20230278983-A1 INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2023-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OXER1, OR51E2 ACHE 889/4885ELANE 3511/4885ALDH1A1 32/4885
US-20230278983-A1 INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER CSNK2A1, IDO1, CSNK2A3 ACHE 1305/4885ELANE 4790/4885ALDH1A1 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.