Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390605 | 0.78 | ESR1 (0.35) | DRD1 | |
| SCHEMBL15698817 | 0.76 | DRD1 (0.36) | DRD1 | |
| SCHEMBL17174370 | 0.72 | DRD1 (0.34) | DRD1 | |
| SCHEMBL4482758 | 0.66 | NPC1 (0.32) | — | |
| SCHEMBL16079381 | 0.62 | — | — | |
| SCHEMBL1145215 | 0.59 | MAOB (0.44) | — | |
| SCHEMBL1536350 | 0.58 | ACHE (0.36) | — | |
| SCHEMBL24393382 | 0.57 | NQO2 (0.41) | — | |
| SCHEMBL12926209 | 0.57 | ESR1 (0.36) | — | |
| SCHEMBL19390819 | 0.57 | DRD1 (0.46) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323821-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | Pfizer Inc (US) | 2018-05-23 | — | — | EP | disclosed |