⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16079386 | 0.83 | DGAT1 (0.32) | — | |
| SCHEMBL16077529 | 0.74 | — | — | |
| SCHEMBL13986149 | 0.68 | CCR1 (0.35) | — | |
| SCHEMBL24393382 | 0.65 | NQO2 (0.41) | — | |
| SCHEMBL23599065 | 0.64 | ALDH1A1 (0.39) | — | |
| SCHEMBL8737801 | 0.63 | ALDH1A1 (0.30) | — | |
| SCHEMBL27285112 | 0.63 | KDM4E (0.31) | — | |
| SCHEMBL20171998 | 0.62 | DRD1 (0.32) | — | |
| SCHEMBL17066440 | 0.61 | ACHE (0.39) | — | |
| SCHEMBL13399609 | 0.61 | ACVRL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |
| US-9512148-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150322092-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION (US) | 2015-11-12 | — | — | US | disclosed |
| US-9127024-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2015-09-08 | — | — | US | disclosed |
| US-20140274954-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION | 2014-09-18 | — | — | US | disclosed |