Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15584736 | 0.86 | FLT3 (0.70) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL15585805 | 0.86 | FLT3 (0.70) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL17969617 | 0.86 | FLT3 (0.70) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL20172044 | 0.82 | FLT3 (0.54) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL16450161 | 0.81 | FLT3 (0.56) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL16450121 | 0.81 | FLT3 (0.68) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL15585827 | 0.80 | FLT3 (0.67) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL15585824 | 0.80 | FLT3 (0.67) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL19675944 | 0.80 | FLT3 (0.67) | FLT3SYKAURKAJAK1JAK3 | |
| SCHEMBL16520189 | 0.79 | FLT3 (0.66) | FLT3SYKAURKAJAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323811-A1 | PRODUCTION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND INTERMEDIATE OF SAID NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM Corporation (JP) | 2018-05-23 | — | — | EP | disclosed |