Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21231952 | 0.93 | ELANE (0.40) | ELANELMNAMAPTKMT2AATM | |
| SCHEMBL18806039 | 0.87 | ELANE (0.41) | ELANELMNAGAAMAPTTDP1 | |
| SCHEMBL25570450 | 0.83 | ELANE (0.38) | ELANELMNAGAAMAPTTDP1 | |
| SCHEMBL18806033 | 0.80 | ELANE (0.39) | ELANETDP1KMT2AATMPOLB | |
| SCHEMBL18806020 | 0.79 | ELANE (0.43) | ELANELMNAGAAKMT2AATM | |
| SCHEMBL20172055 | 0.79 | ELANE (0.43) | ELANELMNAGAAMAPTKMT2A | |
| SCHEMBL2123965 | 0.79 | ELANE (0.57) | ELANELMNAGAAMAPTTDP1 | |
| SCHEMBL20172065 | 0.78 | ABL1 (0.46) | LMNAMAPTHPGDKMT2ATSHR | |
| SCHEMBL18806035 | 0.77 | ELANE (0.38) | ELANEMAPTTDP1KMT2AATM | |
| SCHEMBL23255224 | 0.76 | ELANE (0.43) | ELANEKMT2AATMACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162875-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |