Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 11/20 | 0.33 |
| ▸ | DRD2 | P14416 | 8/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24319517 | 0.83 | GBA1 (0.46) | GBA1HTR1ADRD2 | |
| SCHEMBL24319515 | 0.83 | GBA1 (0.46) | GBA1HTR1ADRD2 | |
| SCHEMBL24319642 | 0.83 | GBA1 (0.46) | GBA1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL28684996 | 0.79 | GBA1 (0.40) | GBA1HTR1ADRD2 | |
| Ammonia Solution, Strong SCHEMBL29062066 | 0.79 | GBA1 (0.40) | GBA1HTR1ADRD2CYP2D6TSHR | |
| SCHEMBL18640349 | 0.79 | GBA1 (0.35) | GBA1 | |
| SCHEMBL18501202 | 0.78 | GBA1 (0.39) | GBA1HTR1ADRD2CYP2D6TSHR | |
| SCHEMBL7026043 | 0.74 | S1PR1 (0.49) | DRD2TSHR | |
| SCHEMBL28081479 | 0.73 | S1PR1 (0.41) | GBA1 | |
| Water SCHEMBL28363852 | 0.72 | S1PR1 (0.47) | DRD2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323818-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |