Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 8/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | GNG2 | P59768 | 1/20 | 0.31 |
| ▸ | GNB1 | P62873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17490039 | 0.83 | CDK8 (0.37) | CDK8 | |
| SCHEMBL20172233 | 0.81 | GNG2 (0.40) | CDK8GNG2GNB1 | |
| SCHEMBL17490203 | 0.78 | PIM1 (0.37) | CDK8 | |
| SCHEMBL21415084 | 0.76 | CDK8 (0.38) | CDK8GNG2GNB1 | |
| SCHEMBL29214105 | 0.75 | MAPT (0.40) | CDK8 | |
| SCHEMBL17489707 | 0.75 | CDK8 (0.38) | CDK8 | |
| SCHEMBL20308279 | 0.72 | ALDH1A1 (0.38) | CDK8 | |
| SCHEMBL20307931 | 0.72 | NPC1 (0.45) | — | |
| SCHEMBL20308278 | 0.71 | CDK8 (0.37) | CDK8 | |
| SCHEMBL10043567 | 0.69 | MAPT (0.45) | CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980182-B1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2018-05-23 | — | — | EP | disclosed |