Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20172378 | 0.89 | KDM4E (0.38) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL21415084 | 0.84 | CDK8 (0.38) | — | |
| SCHEMBL20172215 | 0.81 | ADRA2A (0.35) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL20307931 | 0.81 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL29214105 | 0.77 | MAPT (0.40) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL20172209 | 0.76 | HSPA1A (0.36) | SMN1; SMN2KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL17490203 | 0.76 | PIM1 (0.37) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL20308231 | 0.76 | CDK8 (0.35) | KDM4E | |
| SCHEMBL20172208 | 0.76 | ADRA2A (0.35) | LMNAKDM4EMAPTADRA2AADRA2B | |
| SCHEMBL17482930 | 0.74 | EGLN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339395-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Samsung Electronics Co., Ltd. (KR) | 2018-06-27 | — | — | EP | disclosed |
| EP-2980182-B1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2018-05-23 | — | — | EP | disclosed |