Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23942 | 0.92 | TOP1 (0.50) | TOP1ACACAMEN1KMT2ARAB9A | |
| SCHEMBL22434702 | 0.91 | PARP1 (0.44) | TOP1ACACAMEN1KMT2ARAB9A | |
| SCHEMBL12112655 | 0.90 | ACACA (0.51) | TOP1ACACAMEN1KMT2AALDH1A1 | |
| SCHEMBL27752791 | 0.90 | TOP1 (0.49) | TOP1ACACAMEN1KMT2ARAB9A | |
| SCHEMBL12112619 | 0.89 | ACACA (0.45) | TOP1ACACAMEN1KMT2ARAB9A | |
| SCHEMBL10032326 | 0.89 | ACACA (0.45) | TOP1ACACAMEN1KMT2ARAB9A | |
| SCHEMBL10032283 | 0.89 | ACACA (0.45) | TOP1ACACAMEN1KMT2ARAB9A | |
| SCHEMBL25850603 | 0.89 | ACACA (0.45) | TOP1ACACAMEN1KMT2ARAB9A | |
| SCHEMBL3358457 | 0.89 | ACACA (0.50) | TOP1ACACAMEN1KMT2AALDH1A1 | |
| SCHEMBL17899330 | 0.89 | ACACA (0.50) | TOP1ACACAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10629817-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-04-21 | — | — | US | disclosed |
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | KCNB2, KCNB1, GJB2 | TOP1 3480/4885ACACA 3821/4885MEN1 714/4885 |
| US-10629817-B2 | Materials for organic electroluminescent devices | KCNB2, KCNB1, GJB2 | TOP1 3520/4885ACACA 3915/4885MEN1 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.