SCHEMBL20173394

SCHEMBL20173394

CCCCCCCCCCCCC(CCCCCCCCCC)COc1ccc(CCCCc2cc3c(cc(CCCCc4ccc(OCC(CCCCCCCCCC)CCCCCCCCCCCC)cc4)c4ccsc43)c3sccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 3/20 0.43
PLA2G4A P47712 6/20 0.42
S1PR4 O95977 2/20 0.42
S1PR5 Q9H228 2/20 0.42
S1PR2 O95136 1/20 0.42
S1PR3 Q99500 1/20 0.42
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SLCO1B3 Q9NPD5 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
HRH3 Q9Y5N1 1/20 0.35
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20173395 0.80 S1PR1 (0.39) S1PR1PLA2G4AS1PR4S1PR5S1PR2
SCHEMBL20173398 0.79 S1PR1 (0.38) S1PR1PLA2G4AS1PR4S1PR5S1PR2
SCHEMBL20173390 0.78 S1PR1 (0.52) S1PR1PLA2G4AS1PR4S1PR5S1PR2
SCHEMBL20173393 0.78 S1PR1 (0.52) S1PR1PLA2G4AS1PR4S1PR5S1PR2
SCHEMBL20173386 0.75 ALDH1A1 (0.57) S1PR1S1PR4S1PR5S1PR2S1PR3
SCHEMBL30732342 0.75 PRSS1 (0.36) PLA2G4AALDH1A1LMNAKMT2A
SCHEMBL861880 0.75 PRSS1 (0.36) PLA2G4AALDH1A1LMNAKMT2A
SCHEMBL12667477 0.74 PRSS1 (0.35) PLA2G4AALDH1A1LMNACYP3A4KMT2A
SCHEMBL19206981 0.73 GPR35 (0.40) MEN1ALDH1A1CYP3A4KMT2APDE4A
SCHEMBL22579950 0.72 HTR2A (0.56) S1PR1S1PR4S1PR5S1PR2S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180145259-A1 ORGANIC SEMICONDUCTOR ELEMENT, COMPOUND, ORGANIC SEMICONDUCTOR COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC SEMICONDUCTOR FILM FUJIFILM CORPORATION (JP) 2018-05-24 US disclosed