Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20173647 | 0.98 | HPGD (0.54) | HPGDHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL20173650 | 0.95 | ALDH1A1 (0.54) | HPGDHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL20164980 | 0.87 | HPGD (0.59) | HPGDHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL9816479 | 0.85 | HPGD (0.52) | HPGDHSP90AA1HSP90AB1ALDH1A1MEN1 | |
| SCHEMBL6780219 | 0.84 | HPGD (0.57) | HPGDHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL11613230 | 0.84 | HSP90AA1 (0.72) | HPGDHSP90AA1HSP90AB1TDP1MEN1 | |
| SCHEMBL20164970 | 0.79 | GLRA1 (0.59) | HPGDHSP90AA1HSP90AB1ALDH1A1TDP1 | |
| SCHEMBL4300003 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1MEN1HTT | |
| SCHEMBL4598135 | 0.79 | HSP90AA1 (0.52) | HPGDHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL4597513 | 0.78 | HSP90AA1 (0.43) | HPGDHSP90AA1HSP90AB1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10449198-B2 | Method for treating pain | THE UNIVERSITY OF LIVERPOOL (GB) | 2019-10-22 | — | — | US | disclosed |
| US-20180140608-A1 | METHOD | UNIV LIVERPOOL (GB) | 2018-05-24 | — | — | US | disclosed |
| US-20180140608-A1 | METHOD | UNIV LIVERPOOL (GB) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10449198-B2 | Method for treating pain | ACHE, ASAH2, OPRL1 | HPGD 180/4885HSP90AA1 1048/4885HSP90AB1 1034/4885 |
| US-20180140608-A1 | METHOD | ASAH2, ACHE, OPRL1 | HPGD 141/4885HSP90AA1 1655/4885HSP90AB1 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.