Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140451 | 0.78 | TDP1 (0.53) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL23339068 | 0.78 | TDP1 (0.63) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL19051162 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL16443414 | 0.75 | HRH1 (0.43) | ALDH1A1MGLL | |
| SCHEMBL31565710 | 0.72 | IDO1 (0.47) | ALDH1A1 | |
| SCHEMBL13573130 | 0.71 | MEN1 (0.46) | MEN1KMT2AMGLL | |
| SCHEMBL5634061 | 0.70 | TDP1 (0.63) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL12626951 | 0.70 | NR3C1 (0.38) | TDP1 | |
| SCHEMBL12890920 | 0.70 | TDP1 (0.53) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL731016 | 0.69 | TSHR (0.48) | TDP1ALDH1A1TP53TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142137-A1 | AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE SOLID COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME | THE LUBRIZOL CORPORATION | 2018-05-24 | — | — | US | disclosed |