Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.57 |
| ▸ | CTSL | P07711 | 8/20 | 0.57 |
| ▸ | CTSS | P25774 | 7/20 | 0.57 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140126 | 0.87 | ALDH1A1 (0.53) | — | |
| SCHEMBL7140119 | 0.87 | ALDH1A1 (0.53) | — | |
| SCHEMBL11509326 | 0.84 | CTSK (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5707878 | 0.84 | CTSK (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL14017627 | 0.84 | CTSK (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL11658563 | 0.83 | CTSK (0.58) | CTSKCTSLCTSSCTSB | |
| SCHEMBL20174031 | 0.82 | CTSK (0.63) | CTSKCTSLCTSSCTSB | |
| SCHEMBL9156377 | 0.82 | KCNA5 (0.62) | CTSKCTSLCTSSCTSB | |
| SCHEMBL9682622 | 0.82 | CTSK (0.57) | CTSKCTSLCTSSCTSB | |
| SCHEMBL9156373 | 0.82 | KCNA5 (0.62) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094335-A1 | FINE-TUNE MODULATORS OF NEURONAL EXCITABILITY FOR NEUROPSYCHIATRIC DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-05-24 | — | — | WO | disclosed |