Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546729 | 0.85 | ELANE (0.45) | ELANEMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL14717313 | 0.85 | ELANE (0.45) | ELANEMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL9815566 | 0.83 | KDM4E (0.44) | ELANEL3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL2950704 | 0.82 | ELANE (0.46) | ELANEMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL7688111 | 0.81 | ELANE (0.47) | ELANEMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL11424671 | 0.81 | ELANE (0.42) | ELANEMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL11424670 | 0.81 | ELANE (0.42) | ELANEMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL27668892 | 0.81 | PTGS2 (0.49) | ELANEKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL9419997 | 0.80 | ELANE (0.49) | ELANEMTNR1AMTNR1BMAPTALDH1A1 | |
| SCHEMBL27952555 | 0.79 | ELANE (0.41) | ELANEMAPTALDH1A1L3MBTL1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | HENKEL AG & CO. KGAA (DE) | 2019-04-09 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | KRT18, ALDH7A1, ALDH1A2 | ELANE 1509/4885MTNR1A 2389/4885MTNR1B 3219/4885 |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | KRT18, ALDH7A1, ALDH1A2 | ELANE 1509/4885MTNR1A 2389/4885MTNR1B 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.