SCHEMBL20174160

SCHEMBL20174160

C=CC(=O)Oc1ccc(-c2ccc(OC(=O)CCc3ccc(OC(=O)C=C)c(OC(=O)C=C)c3)cc2)cc1F

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.37
FFAR4 Q5NUL3 1/20 0.35
ALOX15 P16050 2/20 0.34
AKR1C3 P42330 5/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
HPGD P15428 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
S1PR5 Q9H228 1/20 0.33
FFAR1 O14842 1/20 0.33
CCR5 P51681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16803374 0.98 THRB (0.42) THRBKMT2AMAPTFFAR4ALOX15
SCHEMBL17719440 0.93 THRB (0.40) THRBKMT2AMAPTFFAR4ALOX15
SCHEMBL17461504 0.92 THRB (0.49) THRBKMT2AMAPTALOX15NPC1
SCHEMBL21556855 0.92 KMT2A (0.42) THRBKMT2AMAPTAKR1C3NPC1
SCHEMBL20105023 0.92 FFAR1 (0.41) THRBKMT2AMAPTALOX15AKR1C3
SCHEMBL18541166 0.92 THRB (0.39) THRBKMT2AMAPTFFAR4ALOX15
SCHEMBL20626667 0.91 ADRB2 (0.43) THRBKMT2AMAPTFFAR4ALOX15
SCHEMBL16803383 0.90 THRB (0.39) THRBKMT2AMAPTALOX15AKR1C3
SCHEMBL21082897 0.90 THRB (0.39) THRBKMT2AMAPTALOX15AKR1C3
SCHEMBL17719436 0.90 THRB (0.39) THRBKMT2AMAPTALOX15AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200301213-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2020-09-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed