Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175201 | 0.89 | PDK2 (0.37) | PDK2NTRK1PLK3MAOANMUR2 | |
| SCHEMBL20175205 | 0.88 | AHR (0.37) | PDK2NTRK1PLK3MAOANMUR2 | |
| SCHEMBL20174739 | 0.85 | NTRK1 (0.40) | NTRK1PLK3MAOANMUR2L3MBTL1 | |
| SCHEMBL20199299 | 0.82 | PDK2 (0.42) | PDK2NTRK1PLK3MAOAMAOB | |
| SCHEMBL16855614 | 0.80 | ALOX5 (0.40) | PDK2MAOAMAOB | |
| SCHEMBL17883218 | 0.80 | PDK2 (0.39) | PDK2MAOAMAOB | |
| SCHEMBL17716721 | 0.80 | CA1 (0.34) | NTRK1PLK3L3MBTL1 | |
| SCHEMBL18582824 | 0.80 | NMUR2 (0.42) | PDK2NTRK1PLK3NMUR2 | |
| SCHEMBL16491720 | 0.80 | PDK2 (0.40) | PDK2NTRK1PLK3MAOAMAOB | |
| SCHEMBL16491662 | 0.78 | PDK2 (0.40) | PDK2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PDK2 651/4885NTRK1 4548/4885PLK3 1825/4885 |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PDK2 651/4885NTRK1 4548/4885PLK3 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.