Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 4/20 | 0.33 |
| ▸ | GABRD | O14764 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.33 |
| ▸ | GABRE | P78334 | 4/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175200 | 0.93 | AHR (0.38) | PDK2NMUR2TNKSGABRPGABRD | |
| SCHEMBL20174745 | 0.87 | NTRK1 (0.37) | NMUR2ALKALOX5 | |
| SCHEMBL20199299 | 0.81 | PDK2 (0.42) | PDK2CA1CA2 | |
| SCHEMBL18034339 | 0.81 | PDK2 (0.38) | PDK2NMUR2TNKSGABRPGABRD | |
| SCHEMBL18034445 | 0.81 | PDK2 (0.38) | PDK2NMUR2TNKSGABRPGABRD | |
| SCHEMBL19395172 | 0.80 | PDK2 (0.37) | PDK2NMUR2TNKSGABRPGABRD | |
| SCHEMBL16232653 | 0.80 | ALOX5 (0.39) | PDK2NMUR2TNKSGABRPGABRD | |
| SCHEMBL19395176 | 0.80 | PDK2 (0.37) | PDK2NMUR2TNKSGABRPGABRD | |
| SCHEMBL20199301 | 0.80 | PDK2 (0.45) | PDK2TNKSCA1CA2 | |
| SCHEMBL15990196 | 0.80 | ALOX5 (0.39) | PDK2NMUR2TNKSGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PDK2 651/4885NMUR2 1779/4885TNKS 3424/4885 |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PDK2 651/4885NMUR2 1779/4885TNKS 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.