Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ESRRG | P62508 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27178222 | 0.88 | SMN1; SMN2 (0.76) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL27178216 | 0.88 | SMN1; SMN2 (0.76) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL27178088 | 0.87 | SMN1; SMN2 (0.75) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28520310 | 0.87 | MAPT (0.76) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL30826121 | 0.87 | SMN1; SMN2 (0.75) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL27178082 | 0.87 | SMN1; SMN2 (0.75) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL1129164 | 0.86 | RAB9A (0.78) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL13791267 | 0.86 | RAB9A (0.78) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL20175460 | 0.85 | MAPT (0.74) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL10802330 | 0.85 | SMN1; SMN2 (0.84) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | KMT2A 3034/4885MEN1 1342/4885RAB9A 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.