SCHEMBL20175719

SCHEMBL20175719

Brc1cc2c3ccccc3n(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-c4ccc(-c5ccccc5)cc4)n3)c2c2sc3ccccc3c12

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 2/20 0.34
▸ PTPRC P08575 1/20 0.33
▸ PTPRF P10586 1/20 0.33
▸ PTPRA P18433 1/20 0.33
▸ PTPRB P23467 1/20 0.33
▸ PTPN6 P29350 1/20 0.33
▸ DUSP3 P51452 1/20 0.33
▸ PTPN12 Q05209 1/20 0.33
▸ LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20175745 0.89 PTPN1 (0.35) PTPN1PTPRCPTPRFPTPRAPTPRB
SCHEMBL27324912 0.88 LIMK1 (0.31) LIMK1
SCHEMBL18101424 0.85 PTPN1 (0.37) PTPN1PTPRCPTPRFPTPRAPTPRB
SCHEMBL20175713 0.85 ABCG2 (0.39) —
SCHEMBL27324941 0.84 LIMK1 (0.31) LIMK1
SCHEMBL21707294 0.83 TNKS (0.32) LIMK1
SCHEMBL18086397 0.83 TNKS (0.32) LIMK1
SCHEMBL19985956 0.82 MEN1 (0.31) LIMK1
SCHEMBL16521240 0.82 TNKS (0.33) LIMK1
SCHEMBL15625597 0.82 TNKS (0.33) LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 PTPN1 3017/4885PTPRC 3605/4885PTPRF 3242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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