⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307850 | 0.81 | — | — | |
| SCHEMBL23219630 | 0.74 | — | — | |
| SCHEMBL2631135 | 0.73 | — | — | |
| SCHEMBL19243528 | 0.71 | TRPA1 (0.39) | — | |
| SCHEMBL22649255 | 0.71 | — | — | |
| SCHEMBL23956491 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL20347814 | 0.71 | — | — | |
| SCHEMBL22456775 | 0.71 | — | — | |
| SCHEMBL329436 | 0.71 | — | — | |
| SCHEMBL5383072 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| US-20180141909-A1 | ROR GAMMA (RORY) MODULATORS | LEAD PHARMA HOLDING B.V. (NL) | 2018-05-24 | — | — | US | disclosed |