Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176115 | 0.83 | NPC1 (0.44) | SLC6A2FDPSCYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1446791 | 0.73 | SMN1; SMN2 (0.53) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL28105527 | 0.72 | SMN1; SMN2 (0.47) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL28352359 | 0.72 | SMN1; SMN2 (0.47) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL23572607 | 0.72 | SMN1; SMN2 (0.47) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL2036359 | 0.72 | SMN1; SMN2 (0.52) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL2032810 | 0.72 | SMN1; SMN2 (0.52) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL20176094 | 0.71 | NPC1 (0.46) | SMN1; SMN2FDPSCYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1275761 | 0.71 | SMN1; SMN2 (0.55) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL3361395 | 0.71 | SMN1; SMN2 (0.55) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450331-B2 | Functionalized cyanosilane and synthesis method and use thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2019-10-22 | — | — | US | disclosed |
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | EAST CHINA NORMAL UNIVERSITY (CN) | 2018-05-24 | — | — | US | disclosed |
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | EAST CHINA NORMAL UNIVERSITY (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | NCLN, PNN, MB | TRPA1 3007/4885SMN1; SMN2 762/4885HIF1A 2913/4885 |
| US-10450331-B2 | Functionalized cyanosilane and synthesis method and use thereof | NCLN, PNN, MB | TRPA1 3007/4885SMN1; SMN2 762/4885HIF1A 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.