Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20163042 | 0.90 | HDAC1 (0.53) | HDAC1HDAC2BACE1KITWNT3A | |
| SCHEMBL20163086 | 0.76 | MAPT (0.50) | NAMPTMAPTALDH1A1GPR119CKS1B | |
| SCHEMBL29803448 | 0.75 | NAMPT (0.55) | KITWNT3ANAMPTMAPTALDH1A1 | |
| SCHEMBL20163040 | 0.75 | CTSS (0.42) | BACE1KITWNT3ACTSSCTSK | |
| SCHEMBL5542227 | 0.74 | GPR119 (0.65) | CTSSCTSKNAMPTMAPTALDH1A1 | |
| SCHEMBL20163022 | 0.74 | HDAC2 (0.52) | HDAC1HDAC2BACE1KITCTSS | |
| SCHEMBL20163144 | 0.74 | MAPT (0.48) | NAMPTMAPTALDH1A1GPR119MEN1 | |
| SCHEMBL13164532 | 0.74 | GPR119 (0.61) | KITCTSSCTSKNAMPTMAPT | |
| SCHEMBL23961022 | 0.73 | BACE1 (0.51) | HDAC2BACE1KITWNT3ACTSS | |
| SCHEMBL20207460 | 0.72 | BACE1 (0.51) | HDAC1HDAC2BACE1KITWNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | REGENACY PHARMACEUTICALS, LLC | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | HDAC1, HDAC2, HDAC11 | HDAC1 1/4885HDAC2 2/4885BACE1 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.