SCHEMBL20176510

SCHEMBL20176510

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc(-c6ccc7c(c6)c6c8ccccc8ccc6n7-c6ccccc6)cc5)nc4)c4ccccc34)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 2/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MTOR P42345 1/20 0.33
MAPT P10636 2/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK10 P53779 1/20 0.32
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
HPGDS O60760 1/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26160969 1.00 PTGES (0.33) PTGESJAK2JAK3KDM4EATM
SCHEMBL26161136 0.97 JAK2 (0.36) PTGESJAK2JAK3KDM4EATM
SCHEMBL26160966 0.96 JAK2 (0.37) PTGESJAK2JAK3KDM4EATM
SCHEMBL26161233 0.95 JAK2 (0.34) PTGESJAK2JAK3KDM4EATM
SCHEMBL26161236 0.95 JAK2 (0.34) PTGESJAK2JAK3KDM4EATM
SCHEMBL26161053 0.95 JAK2 (0.34) PTGESJAK2JAK3KDM4EATM
SCHEMBL26161051 0.94 JAK2 (0.34) PTGESJAK2JAK3KDM4EATM
SCHEMBL20176512 0.89 PTGES (0.32) PTGESJAK2JAK3KDM4EATM
SCHEMBL26160965 0.88 PTGES (0.32) PTGESJAK2JAK3KDM4EATM
SCHEMBL26161232 0.87 PTGES (0.31) PTGESKDM4EATML3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 PTGES 1627/4885JAK2 3546/4885JAK3 3390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.