SCHEMBL20176540

SCHEMBL20176540

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc6c(c5)c5cc7ccccc7cc5n6-c5ccccc5)nc4)c4ccccc34)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.37
ESR2 Q92731 3/20 0.37
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 1/20 0.34
MTOR P42345 2/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
HPGDS O60760 1/20 0.33
AXL P30530 1/20 0.33
CDK8 P49336 1/20 0.33
TNIK Q9UKE5 1/20 0.33
GSK3B P49841 2/20 0.32
GSK3A P49840 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
DYRK1A Q13627 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26160960 0.99 ESR1 (0.38) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL26160963 0.97 ESR1 (0.36) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL20176503 0.97 ESR1 (0.36) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL26161048 0.93 ESR1 (0.37) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL20176490 0.93 ESR1 (0.37) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL26161230 0.93 ESR1 (0.37) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL26161228 0.93 ESR1 (0.37) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL26160959 0.92 ESR1 (0.38) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL26161046 0.92 ESR1 (0.38) ESR1ESR2KDM4EATML3MBTL1
SCHEMBL20176502 0.91 L3MBTL1 (0.45) KDM4EATML3MBTL1KMT2AJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 ESR1 310/4885ESR2 934/4885KDM4E 2080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.