Sugi Predict

Sugi Predict / Compounds / SCHEMBL20176547

SCHEMBL20176547

SCHEMBL20176547

Brc1ccc(-c2c3ccccc3c(-c3ccncc3)c3ccccc23)cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 2/20 0.47
▸ L3MBTL1 Q9Y468 3/20 0.41
▸ IMPDH2 P12268 2/20 0.40
▸ MAPK14 Q16539 6/20 0.40
▸ NOTUM Q6P988 1/20 0.39
▸ PDGFRB P09619 1/20 0.39
▸ PDGFRA P16234 1/20 0.39
▸ MAPK13 O15264 1/20 0.37
▸ MAPK12 P53778 1/20 0.37
▸ MAPK11 Q15759 1/20 0.37
▸ KDR P35968 1/20 0.36
▸ KDM4E B2RXH2 3/20 0.35
▸ MAPT P10636 3/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ CYP1A2 P05177 2/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776275 1.00 CYP19A1 (0.47) CYP19A1L3MBTL1IMPDH2MAPK14NOTUM
SCHEMBL25228669 0.88 PIK3CA (0.46) CYP19A1IMPDH2NOTUMPDGFRBPDGFRA
SCHEMBL25204761 0.88 PIK3CA (0.46) CYP19A1IMPDH2NOTUMPDGFRBPDGFRA
SCHEMBL25210264 0.87 L3MBTL1 (0.46) CYP19A1L3MBTL1KDRKDM4EMAPT
SCHEMBL29776270 0.85 NPC1 (0.47) CYP19A1L3MBTL1KDM4EMAPTMAPK1
SCHEMBL20176443 0.85 NPC1 (0.47) CYP19A1L3MBTL1KDM4EMAPTMAPK1
SCHEMBL15977944 0.80 NOTUM (0.59) IMPDH2MAPK14NOTUMMAPK13MAPK12
SCHEMBL11910167 0.80 NOTUM (0.57) IMPDH2MAPK14NOTUMMAPK13MAPK12
SCHEMBL29538964 0.80 NOTUM (0.57) IMPDH2MAPK14NOTUMMAPK13MAPK12
SCHEMBL27862692 0.79 NOTUM (0.48) L3MBTL1IMPDH2MAPK14NOTUMMAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 — — US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 — — US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 — — US disclosed
CN-110023305-B Organic light-emitting compound and organic electroluminescent element using same 索路思高新材料有限公司 2022-08-09 — — CN disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 CYP19A1 1559/4885L3MBTL1 869/4885IMPDH2 1406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.