Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598927 | 0.82 | POLB (0.50) | ANO1USP30CNR1CNR2BTK | |
| SCHEMBL16177328 | 0.82 | POLB (0.50) | ANO1USP30CNR1CNR2BTK | |
| SCHEMBL16177330 | 0.82 | POLB (0.50) | ANO1USP30CNR1CNR2BTK | |
| SCHEMBL21386781 | 0.82 | BTK (0.50) | USP30BTKPIK3CDJAK3 | |
| SCHEMBL22909230 | 0.82 | BTK (0.50) | USP30BTKPIK3CDJAK3 | |
| SCHEMBL21599048 | 0.82 | ANO1 (0.47) | ANO1USP30CNR1CNR2BTK | |
| SCHEMBL31227197 | 0.80 | BTK (0.47) | ANO1USP30CNR1CNR2BTK | |
| SCHEMBL16187368 | 0.79 | USP30 (0.50) | USP30BTKPIM1PIM2PIK3CD | |
| SCHEMBL31227063 | 0.79 | ANO1 (0.45) | ANO1USP30CNR1CNR2BTK | |
| SCHEMBL31227974 | 0.79 | BTK (0.45) | ANO1USP30CNR1CNR2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092047-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | JOINT STOCK COMPANY "BIOCAD" (RU) | 2018-05-24 | — | — | WO | disclosed |