Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.36 |
| ▸ | RXRB | P28702 | 8/20 | 0.35 |
| ▸ | RARB | P10826 | 6/20 | 0.35 |
| ▸ | RARG | P13631 | 5/20 | 0.35 |
| ▸ | RXRG | P48443 | 4/20 | 0.35 |
| ▸ | RARA | P10276 | 4/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15120396 | 0.96 | RXRA (0.36) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL29726395 | 0.96 | RXRA (0.38) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL476929 | 0.96 | RXRA (0.38) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL818606 | 0.93 | RXRA (0.38) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL18904618 | 0.91 | RXRA (0.40) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL13672540 | 0.89 | RXRA (0.34) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL14345101 | 0.89 | RXRA (0.35) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL21617582 | 0.86 | KDM4E (0.35) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL4008392 | 0.86 | RXRA (0.34) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL25373674 | 0.85 | CYP26A1 (0.42) | RXRARXRBRARBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017435-B2 | Process for the preparation of a phenylindan compound | IGH RESINS ITALIA S.R.L. | 2018-07-10 | — | — | US | disclosed |
| US-20180141882-A1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | IGM RESINS ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017435-B2 | Process for the preparation of a phenylindan compound | CYP1A1, HPD, CYP1B1 | RXRA 2540/4885RXRB 2983/4885RARB 3939/4885 |
| US-20180141882-A1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | CYP1A1, HPD, CYP1B1 | RXRA 2540/4885RXRB 2983/4885RARB 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.