Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 11/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176370 | 0.77 | SLC6A2 (0.31) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL22837294 | 0.76 | SLC6A2 (0.31) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL20176407 | 0.73 | SLC6A2 (0.41) | SLC6A2SLC6A3SLC6A4HTR1ATRPA1 | |
| SCHEMBL8966569 | 0.73 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4HTR1ATRPA1 | |
| SCHEMBL24180233 | 0.71 | SLC6A2 (0.70) | SLC6A2SLC6A3SLC6A4HTR1A | |
| SCHEMBL20176345 | 0.70 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4HTR1A | |
| SCHEMBL26933114 | 0.69 | SLC6A2 (0.62) | SLC6A2SLC6A3SLC6A4HTR1A | |
| Hydrochloric Acid SCHEMBL20165490 | 0.69 | SLC6A2 (0.96) | SLC6A2SLC6A3SLC6A4HTR1A | |
| SCHEMBL26933110 | 0.69 | SLC6A2 (0.62) | SLC6A2SLC6A3SLC6A4HTR1A | |
| SCHEMBL27859496 | 0.68 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4HTR1ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10875829-B1 | Azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission | INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) | 2020-12-29 | — | — | US | disclosed |
| WO-2018091687-A1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875829-B1 | Azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission | SLC18A1, CHRM1, CHRM2 | SLC6A2 21/4885SLC6A3 15/4885SLC6A4 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.