SCHEMBL20176688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29776150	1.00	ENPP1 (0.43)	ENPP1ENPP3HDAC8HDAC6MEN1
	SCHEMBL15158541	0.88	MEN1 (0.44)	ENPP1ENPP3MEN1KMT2ALMNA
	SCHEMBL28491556	0.85	HDAC8 (0.50)	ENPP1ENPP3HDAC8HDAC6CA12
	SCHEMBL1534980	0.83	CYP11B2 (0.48)	MEN1KMT2ALMNAMAPTCYP11B1
	SCHEMBL29776157	0.82	NPC1 (0.47)	MAPTCA2MCL1
	SCHEMBL20176784	0.82	NPC1 (0.47)	MAPTCA2MCL1
	SCHEMBL20176544	0.81	MAPK1 (0.43)	MEN1KMT2ALMNAMAPTCYP11B1
	SCHEMBL29776268	0.81	MAPK1 (0.43)	MEN1KMT2ALMNAMAPTCYP11B1
	SCHEMBL20909418	0.81	ENPP1 (0.43)	ENPP1ENPP3HDAC8HDAC6CA12
	SCHEMBL20176684	0.81	HDAC8 (0.44)	ENPP1ENPP3HDAC8HDAC6CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.