Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176720 | 0.91 | RARB (0.30) | RARB | |
| SCHEMBL20176723 | 0.88 | — | — | |
| SCHEMBL20182253 | 0.86 | RARB (0.32) | RARBS1PR1S1PR3 | |
| SCHEMBL20182250 | 0.83 | ENPP1 (0.43) | ENPP1 | |
| SCHEMBL20182254 | 0.83 | — | — | |
| SCHEMBL20176718 | 0.82 | GCGR (0.36) | RARBGCGRS1PR1 | |
| SCHEMBL20176717 | 0.80 | KDM4E (0.41) | RARBHSD11B1 | |
| SCHEMBL20176734 | 0.79 | RARB (0.37) | RARBGCGR | |
| SCHEMBL20176725 | 0.77 | RARB (0.45) | RARBGCGRS1PR1S1PR3 | |
| SCHEMBL20176722 | 0.76 | RARB (0.34) | RARBGCGRS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142153-A1 | THIADIAZOLOQUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |