Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | GCGR | P47871 | 9/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | MPL | P40238 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18217161 | 0.88 | RARB (0.34) | RARBGCGRS1PR1S1PR3 | |
| SCHEMBL18217286 | 0.86 | RARB (0.34) | RARBGCGR | |
| SCHEMBL20176722 | 0.85 | RARB (0.34) | RARBGCGRS1PR1 | |
| SCHEMBL18418545 | 0.85 | RARB (0.53) | RARBGCGRRARARARGS1PR1 | |
| SCHEMBL25070534 | 0.82 | RARB (0.31) | RARBGCGR | |
| SCHEMBL25070666 | 0.81 | — | — | |
| SCHEMBL17694335 | 0.80 | RARB (0.48) | RARBGCGRRARARARGS1PR1 | |
| SCHEMBL25070667 | 0.79 | GCGR (0.31) | GCGR | |
| SCHEMBL25070429 | 0.79 | RARB (0.35) | RARBGCGRS1PR1S1PR3 | |
| SCHEMBL25070664 | 0.78 | CRHR1 (0.32) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142153-A1 | THIADIAZOLOQUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |