Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837291 | 0.88 | DRD2 (0.31) | DRD2 | |
| SCHEMBL20165875 | 0.81 | DRD2 (0.31) | DRD2 | |
| SCHEMBL20166163 | 0.79 | DRD2 (0.36) | DRD2 | |
| SCHEMBL20165500 | 0.75 | LMNA (0.31) | — | |
| SCHEMBL20165486 | 0.75 | DRD2 (0.40) | DRD2 | |
| SCHEMBL20168884 | 0.73 | DRD2 (0.32) | DRD2 | |
| SCHEMBL20165484 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL20176661 | 0.72 | SLC6A4 (0.44) | SCN1ASCN8A | |
| SCHEMBL20165485 | 0.71 | DRD2 (0.32) | DRD2 | |
| SCHEMBL20168879 | 0.71 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091687-A1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) | 2018-05-24 | — | — | WO | disclosed |