SCHEMBL20176899

SCHEMBL20176899

O=c1ccn([C@H]2C[C@@H](OP(=O)(O)O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.60
P2RY6 Q15077 7/20 0.51
P2RY2 P41231 8/20 0.50
P2RY4 P51582 4/20 0.50
P2RY14 Q15391 1/20 0.49
TYMS P04818 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5032187 1.00 DUT (0.60) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL2811543 0.92 DUT (0.61) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL26757474 0.89 DUT (0.54) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL2056795 0.89 DUT (0.54) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL4314050 0.89 DUT (0.54) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL26757480 0.89 DUT (0.54) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL7039715 0.89 DUT (0.54) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL20176896 0.88 DUT (0.57) DUTP2RY6P2RY2P2RY4P2RY14
SCHEMBL24137156 0.87 DUT (0.56) DUTP2RY6P2RY2P2RY4TYMS
SCHEMBL18538844 0.87 DUT (0.56) DUTP2RY6P2RY2P2RY4TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11821026-B2 Chemical compositions and methods of using same NANOSTRING TECHNOLOGIES, INC. (US) 2023-11-21 US disclosed
US-11821026-B2 Chemical compositions and methods of using same NANOSTRING TECHNOLOGIES, INC. (US) 2023-11-21 US disclosed
US-20230366012-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME BRUKER SPATIAL BIOLOGY, INC. 2023-11-16 US disclosed
US-20230366012-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME BRUKER SPATIAL BIOLOGY, INC. 2023-11-16 US disclosed
US-20230257800-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2023-08-17 US disclosed
US-20230257800-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2023-08-17 US disclosed
US-20230220461-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2023-07-13 US disclosed
US-20230220461-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2023-07-13 US disclosed
US-11549139-B2 Chemical compositions and methods of using same NANOSTRING TECHNOLOGIES, INC. (US) 2023-01-10 US disclosed
US-10415080-B2 Chemical compositions and methods of using same NANOSTRING TECHNOLOGIES, INC. (US) 2019-09-17 US disclosed
US-20180142286-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2018-05-24 US disclosed
US-20180142286-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2018-05-24 US disclosed