Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.50 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26757474 | 1.00 | DUT (0.54) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL2056795 | 1.00 | DUT (0.54) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL4314050 | 1.00 | DUT (0.54) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL26757480 | 1.00 | DUT (0.54) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL29431049 | 0.91 | DUT (0.56) | DUTP2RY2P2RY6P2RY14P2RY4 | |
| SCHEMBL19025152 | 0.91 | DUT (0.50) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL31342817 | 0.89 | DUT (0.48) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL20176899 | 0.89 | DUT (0.60) | DUTP2RY2P2RY6P2RY14P2RY4 | |
| SCHEMBL5032187 | 0.89 | DUT (0.60) | DUTP2RY2P2RY6P2RY14P2RY4 | |
| SCHEMBL25397715 | 0.86 | SLC28A1 (0.52) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891373-B1 | METHOD AND COMPOUNDS FOR INHIBITION OF RIBONUCLEASES | ENDOWMENT FOR RES IN HUMAN BIO (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-0891373-A1 | METHOD AND COMPOUNDS FOR INHIBITION OF RIBONUCLEASES | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5852001-A | Method and compounds for inhibition of ribonucleases | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY (US) | 1998-12-22 | — | — | US | disclosed |
| WO-1998028321-A1 | METHOD AND COMPOUNDS FOR INHIBITION OF RIBONUCLEASES | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 1998-07-02 | — | — | WO | disclosed |