SCHEMBL20176937

SCHEMBL20176937

Brc1ccc(-c2c3ccccc3c(-c3ccc(-c4ccccc4)c4ccccc34)c3ccccc23)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK4 O00444 1/20 0.41
AURKA O14965 1/20 0.41
JAK2 O60674 1/20 0.41
ROCK2 O75116 1/20 0.41
PRKD3 O94806 1/20 0.41
MAP4K4 O95819 1/20 0.41
PRKCG P05129 1/20 0.41
INSR P06213 1/20 0.41
CDK1 P06493 1/20 0.41
FES P07332 1/20 0.41
IGF1R P08069 1/20 0.41
ROS1 P08922 1/20 0.41
FGFR1 P11362 1/20 0.41
PHKG2 P15735 1/20 0.41
FER P16591 1/20 0.41
FLT1 P17948 1/20 0.41
CDK2 P24941 1/20 0.41
MARK3 P27448 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776344 1.00 PLK4 (0.41) PLK4AURKAJAK2ROCK2PRKD3
SCHEMBL20176544 0.86 MAPK1 (0.43) PLK4AURKAJAK2ROCK2PRKD3
SCHEMBL29776268 0.86 MAPK1 (0.43) PLK4AURKAJAK2ROCK2PRKD3
SCHEMBL12230985 0.84 MEN1 (0.40) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL29776157 0.83 NPC1 (0.47) PLK4AURKAJAK2ROCK2PRKD3
SCHEMBL20176784 0.83 NPC1 (0.47) PLK4AURKAJAK2ROCK2PRKD3
SCHEMBL15158541 0.81 MEN1 (0.44) NPC1RAB9ASMN1; SMN2MAPK1MAPT
SCHEMBL29776150 0.79 ENPP1 (0.43) MAPTMEN1LMNAKMT2ATNF
SCHEMBL20176688 0.79 ENPP1 (0.43) MAPTMEN1LMNAKMT2ATNF
SCHEMBL25198649 0.77 NPC1 (0.41) PLK4AURKAJAK2ROCK2PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
CN-110023305-B Organic light-emitting compound and organic electroluminescent element using same 索路思高新材料有限公司 2022-08-09 CN disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 PLK4 4363/4885AURKA 2447/4885JAK2 3546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.