SCHEMBL20177057

SCHEMBL20177057

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccccc4)c(-n4c5ccccc5c5c6c7ccccc7n(-c7ccccc7)c6ccc54)c3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 2/20 0.42
KDM4E B2RXH2 1/20 0.42
KMT2A Q03164 5/20 0.35
IL1R1 P14778 1/20 0.35
MEN1 O00255 4/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
PTGER4 P35408 1/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
ACP1 P24666 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20177054 0.93 L3MBTL1 (0.41) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL20177060 0.91 L3MBTL1 (0.40) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL24025150 0.90 KDM4E (0.41) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL20177053 0.90 L3MBTL1 (0.46) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL21147591 0.90 L3MBTL1 (0.46) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL18126018 0.89 L3MBTL1 (0.47) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL24025051 0.89 KDM4E (0.40) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL23510100 0.89 L3MBTL1 (0.45) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL25800001 0.89 MEN1 (0.33) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL25799977 0.89 MEN1 (0.33) L3MBTL1ATMKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10833276-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-10 US disclosed
US-20180145262-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-05-24 US disclosed
US-20180145262-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833276-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, TYR L3MBTL1 239/4885ATM 590/4885KDM4E 3046/4885
US-20180145262-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, TYR L3MBTL1 239/4885ATM 590/4885KDM4E 3046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.