Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18577823 | 0.95 | SMPD1 (0.45) | FDPSSMPD1TSHRTHRBDNM1 | |
| SCHEMBL21180176 | 0.95 | SMPD1 (0.45) | FDPSSMPD1TSHRTHRBDNM1 | |
| SCHEMBL28582904 | 0.95 | SMPD1 (0.45) | FDPSSMPD1TSHRTHRBDNM1 | |
| Hydrochloric Acid SCHEMBL6032000 | 0.92 | SMPD1 (0.44) | FDPSSMPD1TSHRTHRBDNM1 | |
| Bromide SCHEMBL28983796 | 0.92 | SMPD1 (0.44) | FDPSSMPD1TSHRTHRBDNM1 | |
| Hydrochloric Acid SCHEMBL28970149 | 0.92 | SMPD1 (0.44) | FDPSSMPD1TSHRTHRBDNM1 | |
| SCHEMBL17800822 | 0.84 | FDPS (0.38) | FDPSSMPD1TSHR | |
| SCHEMBL18462070 | 0.78 | FDPS (0.44) | FDPSSMPD1TSHRTHRBDNM1 | |
| SCHEMBL22703594 | 0.78 | FDPS (0.44) | FDPSSMPD1TSHRTHRBDNM1 | |
| SCHEMBL28904157 | 0.77 | FDPS (0.36) | FDPSSMPD1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10967068-B2 | Stability-modulating linkers for use with antibody drug conjugates | PFIZER INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20180140714-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | PFIZER INC. (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10967068-B2 | Stability-modulating linkers for use with antibody drug conjugates | FCGR2A, FCGRT, FCGR1A | FDPS 4105/4885SMPD1 1313/4885TSHR 1692/4885 |
| US-20180140714-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | FCGR2A, FCGRT, FCGR1A | FDPS 4105/4885SMPD1 1313/4885TSHR 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.