Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 8/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15337772 | 0.81 | KRAS (0.34) | GAASCDMELKCYP3A4MAPK1 | |
| SCHEMBL16117725 | 0.73 | KRAS (0.48) | GAAMELK | |
| SCHEMBL16117728 | 0.72 | BTK (0.34) | GAASCDCYP3A4MAPK1CYP2C19 | |
| SCHEMBL16122857 | 0.70 | ADRA2A (0.45) | GAA | |
| SCHEMBL20177319 | 0.70 | EGLN1 (0.55) | GAAEGLN1CYP3A4SMN1; SMN2 | |
| SCHEMBL16117708 | 0.69 | CCNK (0.37) | GAACYP3A4MAPK1CYP2C19SMN1; SMN2 | |
| SCHEMBL16117723 | 0.69 | KRAS (0.47) | GAA | |
| SCHEMBL15337877 | 0.66 | SMYD3 (0.38) | GAASCDMELKSMN1; SMN2 | |
| SCHEMBL18466194 | 0.65 | BTK (0.50) | KDM1AMAOA | |
| SCHEMBL16117724 | 0.64 | KRAS (0.54) | GAASCDEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092723-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |