Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | UGCG | Q16739 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15337724 | 0.79 | EGLN1 (0.48) | EGLN1ALDH1A1ATMEPHX2GAA | |
| SCHEMBL6321530 | 0.73 | MRGPRX4 (0.49) | ALDH1A1ATMPOLBGAALMNA | |
| SCHEMBL21387748 | 0.72 | TAS1R3 (0.43) | EGLN1ALDH1A1ATMPOLBGAA | |
| SCHEMBL18466194 | 0.72 | BTK (0.50) | EPHX2 | |
| SCHEMBL13873466 | 0.72 | EPHX2 (0.78) | EPHX2 | |
| SCHEMBL5841965 | 0.71 | MRGPRX4 (0.54) | EGLN1ALDH1A1POLBGAALMNA | |
| SCHEMBL11935246 | 0.71 | PTGER4 (0.47) | ALDH1A1ATMMAPTSMN1; SMN2MEN1 | |
| SCHEMBL13438926 | 0.71 | PTGER4 (0.47) | ALDH1A1ATMMAPTSMN1; SMN2MEN1 | |
| SCHEMBL24460040 | 0.70 | GAA (0.51) | ALDH1A1POLBGAAMAPTSMN1; SMN2 | |
| SCHEMBL20177322 | 0.70 | GAA (0.36) | EGLN1GAASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092723-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |