Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376876 | 0.86 | HTR2A (0.44) | L3MBTL1PTGS2MAPK1ACHEMAPT | |
| SCHEMBL10448890 | 0.83 | L3MBTL1 (0.40) | L3MBTL1PTGS2MAPK1ACHEMAPT | |
| SCHEMBL5792086 | 0.80 | GAA (0.49) | L3MBTL1ACHEMAPT | |
| SCHEMBL6715720 | 0.77 | L3MBTL1 (0.48) | L3MBTL1PTGS2MAPK1ACHEMAPT | |
| SCHEMBL26090280 | 0.77 | BCHE (0.38) | ACHECYP3A4 | |
| SCHEMBL16865515 | 0.77 | BCHE (0.38) | ACHECYP3A4 | |
| SCHEMBL11963636 | 0.77 | MAPT (0.47) | L3MBTL1PTGS2MAPK1ACHEMAPT | |
| SCHEMBL28134390 | 0.77 | ACHE (0.45) | L3MBTL1PTGS2ACHEMAPTCYP3A4 | |
| SCHEMBL2783924 | 0.77 | MAPT (0.47) | L3MBTL1PTGS2MAPK1ACHEMAPT | |
| SCHEMBL11963646 | 0.77 | MAPT (0.47) | L3MBTL1PTGS2MAPK1ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094195-A1 | METHODS FOR DIRECTED FOLDING ASSEMBLY OR DIMERIZATION OF PROTEINS BY TEMPLATED ASSEMBLY REACTIONS | TRIBIOTICA LLC (US) | 2018-05-24 | — | — | WO | disclosed |