Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179093 | 0.97 | SLC7A5 (0.40) | SLC7A5SCN9ALARS1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7866738 | 0.81 | SLC7A5 (0.41) | SLC7A5SCN9ALARS1ALDH1A1MAPT | |
| SCHEMBL18088732 | 0.80 | SLC7A5 (0.47) | SLC7A5SCN9ALARS1ALDH1A1MAPT | |
| Leu-Leu SCHEMBL13737576 | 0.80 | ALDH1A1 (0.60) | SLC7A5ALDH1A1MAPTLAP3MEN1 | |
| Leu-Leu SCHEMBL235250 | 0.80 | ALDH1A1 (0.60) | SLC7A5ALDH1A1MAPTLAP3MEN1 | |
| SCHEMBL10363299 | 0.80 | SLC7A5 (0.47) | SLC7A5SCN9ALARS1ALDH1A1MAPT | |
| Leu-Leu SCHEMBL6044006 | 0.80 | ALDH1A1 (0.60) | SLC7A5ALDH1A1MAPTLAP3MEN1 | |
| Leu-Leu SCHEMBL235249 | 0.80 | ALDH1A1 (0.60) | SLC7A5ALDH1A1MAPTLAP3MEN1 | |
| SCHEMBL10363301 | 0.80 | SLC7A5 (0.47) | SLC7A5SCN9ALARS1ALDH1A1MAPT | |
| Leu-Leu SCHEMBL29401942 | 0.80 | ALDH1A1 (0.60) | SLC7A5ALDH1A1MAPTLAP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092723-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |
| WO-2018092725-A1 | p53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |