Leu-Leu

Leu-Leu

SCHEMBL235249

CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
MAPT P10636 1/20 0.58
SLC7A5 Q01650 1/20 0.57
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
KMT2A Q03164 1/20 0.56
LAP3 P28838 3/20 0.56
FOLH1 Q04609 2/20 0.50
LTA4H P09960 1/20 0.50
MME P08473 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leu-Leu SCHEMBL11140120 1.00 ALDH1A1 (0.60) ALDH1A1MAPTSLC7A5MEN1LMNA
Leu-Leu SCHEMBL29401942 1.00 ALDH1A1 (0.60) ALDH1A1MAPTSLC7A5MEN1LMNA
Leu-Leu SCHEMBL18774992 1.00 ALDH1A1 (0.60) ALDH1A1MAPTSLC7A5MEN1LMNA
Leu-Leu SCHEMBL6044006 1.00 ALDH1A1 (0.60) ALDH1A1MAPTSLC7A5MEN1LMNA
Leu-Leu SCHEMBL235250 1.00 ALDH1A1 (0.60) ALDH1A1MAPTSLC7A5MEN1LMNA
Leu-Leu SCHEMBL13737576 1.00 ALDH1A1 (0.60) ALDH1A1MAPTSLC7A5MEN1LMNA
Leu-Leu SCHEMBL30771444 0.98 ALDH1A1 (0.58) ALDH1A1MAPTSLC7A5MEN1LMNA
Leu-Leu SCHEMBL29400696 0.98 ALDH1A1 (0.58) ALDH1A1MAPTSLC7A5MEN1LMNA
SCHEMBL2722888 0.96 ALDH1A1 (0.56) ALDH1A1MAPTSLC7A5MEN1LMNA
SCHEMBL1019805 0.96 ALDH1A1 (0.56) ALDH1A1MAPTSLC7A5MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119861198-A Plasma metabolic marker combinations for distinguishing early lung cancer from pneumonia 哈尔滨脉图精准技术有限公司 2025-04-22 CN claimed
US-20240400468-A1 Bionutritional Compositions for Plants and Soils ENVIROKURE, INCORPORATED (US) 2024-12-05 US claimed
CN-118465125-A Metabolic marker composition for gastric cancer diagnosis and screening method and application thereof 哈尔滨脉图精准技术有限公司 2024-08-09 CN claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 US claimed
WO-2023009636-A1 BIONUTRITIONAL COMPOSITIONS FOR PLANTS AND SOILS ENVIROKURE, INCORPORATED (US) 2023-02-02 WO claimed
CN-113156096-A Blood-based biomarkers for diagnosing coronary atherosclerotic disease 全球基因集团有限责任公司 2021-07-23 CN claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 US claimed
US-20190310269-A1 SYSTEMS AND METHODS FOR MEASURING OBESITY USING METABOLOME ANALYSIS HUMAN LONGEVITY, INC. 2019-10-10 US claimed
EP-3478121-A1 METHOD FOR SAMPLING GINGIVAL METABOLITES The Procter and Gamble Company (US) 2019-05-08 EP claimed
US-20180003598-A1 METHODS FOR SAMPLING GINGIVAL METABOLITES THE PROCTER & GAMBLE COMPANY 2018-01-04 US claimed
WO-2018005335-A1 METHOD FOR SAMPLING GINGIVAL METABOLITES THE PROCTER & GAMBLE COMPANY (US) 2018-01-04 WO claimed
EP-3242588-A1 BLOOD BASED BIOMARKERS FOR DIAGNOSING ATHEROSCLEROTIC CORONARY ARTERY DISEASE Global Genomics Group, LLC (US) 2017-11-15 EP claimed
WO-2016151372-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF HYPERGLYCEMIA AND METABOLIC SYNDROME MOHAN M ALAPATI (IN) 2016-09-29 WO claimed
US-20160202239-A1 BLOOD BASED BIOMARKERS FOR DIAGNOSING ATHEROSCLEROTIC CORONARY ARTERY DISEASE Global Genomics Group, LLC 2016-07-14 US claimed
WO-2016112337-A1 BLOOD BASED BIOMARKERS FOR DIAGNOSING ATHEROSCLEROTIC CORONARY ARTERY DISEASE Global Genomics Group, LLC (US) 2016-07-14 WO claimed
EP-0910624-B1 PROCESS FOR PRODUCING AND MULTIPLYING LYMPHOCYTES ALBERT WINFRIED DR (DE) 2004-09-22 EP claimed
EP-0286171-B1 DIPEPTIDASE, ITS ISOLATION FROM LACTIC ACID BACTERIA, ANTIBODIES AGAINST THE DIPEPTIDASE, THE USE OF THE DIPEPTIDASE AND OF THE ANTIBODIES AGAINST IT CAMPINA MELKUNIE B.V. (NL) 1993-03-31 EP claimed
US-4888284-A EXTRACTION USING ION EXCHANGE COLUMN CHROMATOGRAPHY RIJKSUNIVERSITEIT TE GRONINGEN (NL) 1989-12-19 US claimed
EP-0286171-A1 Dipeptidase, its isolation from lactic acid bacteria, antibodies against the dipeptidase, the use of the dipeptidase and of the antibodies against it CAMPINA MELKUNIE B.V. (NL) 1988-10-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160202239-A1 BLOOD BASED BIOMARKERS FOR DIAGNOSING ATHEROSCLEROTIC CORONARY ARTERY DISEASE FABP3, APOB, CAD ALDH1A1 493/4885MAPT 2089/4885SLC7A5 3895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.