Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26583876 | 0.78 | EPHX1 (0.48) | PREPKMT2ADPP4FAPALDH1A1 | |
| SCHEMBL6274117 | 0.78 | EPHX1 (0.53) | PREPKMT2ADPP4FAPALDH1A1 | |
| SCHEMBL6809254 | 0.77 | CHRNB2 (0.35) | TSHREPHX1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6810057 | 0.77 | CHRNB2 (0.35) | TSHREPHX1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6267443 | 0.77 | CHRNB2 (0.35) | TSHREPHX1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6271761 | 0.73 | KMT2A (0.41) | KMT2AALDH1A1EPHX1SMN1; SMN2HSD17B10 | |
| SCHEMBL6273403 | 0.73 | KMT2A (0.34) | KMT2AEPHX1SMN1; SMN2HSD17B10PSMB5 | |
| SCHEMBL6274839 | 0.72 | EPHX1 (0.47) | PREPDPP4FAPALDH1A1EPHX1 | |
| SCHEMBL6273756 | 0.72 | AAK1 (0.43) | PREPDPP4FAPALDH1A1EPHX1 | |
| SCHEMBL15082268 | 0.70 | HTR2C (0.44) | PREPKMT2AMEN1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092723-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |
| WO-2018092725-A1 | p53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |