SCHEMBL20177487

SCHEMBL20177487

COc1cc(F)c([C@@H]2CN3CCON=C3[C@H]2N)c(F)c1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 6/20 0.58
DPP4 P27487 2/20 0.32
FPR1 P21462 5/20 0.32
LRRK2 Q5S007 1/20 0.30
KDM1A O60341 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20177508 0.87 FPR2 (0.46) FPR2LRRK2KDM1A
SCHEMBL20177853 0.86 FPR2 (0.45) FPR2
SCHEMBL20177568 0.84 FPR2 (0.42) FPR2
SCHEMBL20177616 0.84 FPR2 (0.42) FPR2KDM1A
SCHEMBL18264293 0.79 FPR2 (0.75) FPR2FPR1
SCHEMBL18264295 0.79 FPR2 (0.75) FPR2FPR1
SCHEMBL18264324 0.74 FPR2 (1.00) FPR2FPR1
SCHEMBL18264322 0.74 FPR2 (1.00) FPR2FPR1
SCHEMBL20408782 0.74 FPR2 (0.45) FPR2
SCHEMBL20177787 0.73 FPR2 (0.46) FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018092916-A1 NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE 宇部興産株式会社 2018-05-24 WO disclosed