Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | CPS1 | P31327 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177493 | 0.76 | ADRA1A (0.36) | ADRA1ACPS1TAAR1HCRTR1HCRTR2 | |
| SCHEMBL20177558 | 0.74 | GRM2 (0.45) | LMNAFPR2 | |
| SCHEMBL20177825 | 0.73 | ADRA1A (0.61) | ADRA1A | |
| SCHEMBL20177794 | 0.73 | ADRA1A (0.61) | ADRA1A | |
| SCHEMBL18264318 | 0.72 | FPR2 (0.34) | TAAR1FPR2 | |
| SCHEMBL18264320 | 0.72 | FPR2 (0.34) | TAAR1FPR2 | |
| SCHEMBL19559537 | 0.70 | HCRTR1 (0.38) | CPS1HCRTR1HCRTR2FPR2 | |
| SCHEMBL19559422 | 0.70 | HCRTR1 (0.38) | CPS1HCRTR1HCRTR2FPR2 | |
| SCHEMBL18117769 | 0.69 | PDE4A (0.50) | CPS1BRD4HCRTR1HCRTR2 | |
| SCHEMBL19559459 | 0.69 | PDE4A (0.50) | CPS1BRD4HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |