SCHEMBL20177567

SCHEMBL20177567

O=C(N[C@@H]1C(=O)NC[C@H]1c1c(F)cc(Br)cc1F)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 13/20 0.52
FPR1 P21462 10/20 0.52
NAAA Q02083 2/20 0.49
CTSL P07711 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20177510 0.90 FPR2 (0.52) FPR2FPR1NAAACTSL
SCHEMBL20177919 0.89 KDM1A (0.41) FPR2FPR1NAAACTSL
SCHEMBL20177594 0.88 FPR2 (0.59) FPR2FPR1
SCHEMBL29434207 0.88 FPR2 (0.68) FPR2FPR1
SCHEMBL16785438 0.88 FPR2 (0.68) FPR2FPR1
SCHEMBL18106440 0.88 FPR2 (0.68) FPR2FPR1
SCHEMBL20177674 0.87 KDM1A (0.42) FPR2FPR1NAAACTSL
SCHEMBL20177533 0.83 NAAA (0.53) NAAACTSL
SCHEMBL20177601 0.80 FPR2 (0.61) FPR2FPR1
SCHEMBL20177720 0.79 NAAA (0.41) FPR2FPR1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018092916-A1 NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE 宇部興産株式会社 2018-05-24 WO disclosed