Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 4/20 | 0.45 |
| ▸ | FPR1 | P21462 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRD2 | P25440 | 2/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16785452 | 0.89 | FPR2 (0.49) | CA1CA2ACHEKCNQ2FPR2 | |
| SCHEMBL16785365 | 0.87 | FPR2 (0.50) | CA1CA2ACHEKCNQ2FPR2 | |
| SCHEMBL20177608 | 0.84 | FPR2 (0.46) | CA1CA2ACHEKCNQ2FPR2 | |
| SCHEMBL20528327 | 0.82 | FPR2 (0.44) | CA1CA2ACHEKCNQ2FPR2 | |
| SCHEMBL18106440 | 0.80 | FPR2 (0.68) | FPR2FPR1 | |
| SCHEMBL29434207 | 0.80 | FPR2 (0.68) | FPR2FPR1 | |
| SCHEMBL18106745 | 0.80 | CA1 (0.47) | CA1CA2ACHEKCNQ2FPR2 | |
| SCHEMBL29434434 | 0.80 | CA1 (0.47) | CA1CA2ACHEKCNQ2FPR2 | |
| SCHEMBL16785438 | 0.80 | FPR2 (0.68) | FPR2FPR1 | |
| SCHEMBL18106743 | 0.80 | CA1 (0.47) | CA1CA2ACHEKCNQ2FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |